1 million IU/ml | 3 million IU/ml | p Value | |
Topical therapy successful at eliminating CIN | 81% (17/21) | 92% (11/12) | 0.41 |
Median time (months) to CIN resolution (95% confidence interval) (n)* | 2.8 (2.0 to 3.5) (17) | 1.9 (0.0 to 5.4) (11) | 0.55 |
Median time (months) on therapy* (range) (n) | 3.6 (0.9 to 14.7) (17) | 4.3 (1.3 to 10.2) (11) | 0.55 |
Side effects of therapy | 10% (2/21) | 17% (2/12) | |
Ocular discomfort | 2 | 1 | 0.55 |
Photophobia | 0 | 1 | |
Median time (months) of follow-up (range) (n) | 19.7 (3.1 to 116) (21) | 47.4 (1.4 to 86) (12) | 0.53 |
↵* In patients with successful resolution on topical therapy