Table 3

Therapy failures and recurrence of disease in patients treated with topical interferon for conjunctival intraepithelial neoplasm (CIN)

1 million IU/ml3 million IU/mlp Value
Topical therapy alone unsuccessful at eliminating CIN19% (4/21)9% (1/12)0.41
Salvage therapy after failure of topical interferon-α2b
 Surgical removal of lesion20
 Mitomycin C21
Resolution of CIN after salvage therapy100% (4/4)100% (1/1)1.00
CIN recurrence in eyes where topical therapy successful12% (2/17)9% (1/11)0.82