Variable | Patient no. | Mean± SD | ||||||||||||||
1 | 2 | 3 | 4 | 5 | 6 | 7 | ||||||||||
Age (years) | 56 | 21 | 46 | 16 | 23 | 31 | 52 | 36±16 | ||||||||
Autosomal Dominant RP | Y | Y | Y | Y | Y | Y | ||||||||||
Length of VPA treatment (months) | 2 | 2 | 4 | 4 | 4 | 6 | 5 | 4±1 | ||||||||
Mean dose of VPA (mg/day) | 750 | 750 | 500 | 500 | 500 | 500 | 750 | 643±133 | ||||||||
Eye | OD | OS | OD | OS | OD | OS | OD | OS | OD | OS | OD | OS | OD | OS | OD | OS |
Visual Field at baseline (mm2) (isopter V4e) | 192 | 165 | 148 | 107 | 38 | 201 | 562 | 558 | 504 | – | 278 | 450 | 442 | 434 | 309±197 | 319±184 |
Visual Field at follow-up (mm2) | 210 | 187 | 165 | 118 | 96 | 200 | 586 | 594 | 452 | – | 517 | 575 | 448 | 385 | 353±192 | 343±207 |
Visual Acuity at baseline (logMAR) | 1 | 1 | 0.544 | 0.301 | 0.176 | 0.301 | 0 | 0 | 0 | 0.097 | 1.301 | 0.097 | 0.176 | 0.301 | 0.456±0.515 | 0.300±0.332 |
Visual acuity at follow-up (logMAR) | 0.176 | 0.301 | 0.544 | 0.176 | 0.097 | 0.301 | 0 | 0 | 0 | 0.097 | 1 | 0.097 | 0 | 0.097 | 0.260±0.380 | 0.153±0.113 |
LogMAR, logarithm of the minimum angle of resolution; OD, right eye; OS, left eye; RP, retinitis pigmentosa; VPA, valproic acid.