Authors | Year | Questionnaires used (author) | Number of uveitis patients | Uveitis type, number of patients | Results |
Schlaegel and Levitt5 | 1959 | Minnesota Multiphasic Personality Inventory | 49 | AU, AU+PU; granulomatous versus non-granulomatous; severity staging | Significantly higher values of psychopathology in uveitis patients; the location, type and severity of uveitis or sex are not correlated with psycho-pathology. |
Erbaugh and Fajardo6 | 1962 | Personal interview | 71 | No details given | Uveitis patients report more depressive episodes prior to hospitalisation than controls. |
Heaton7 | 1964 | Personal interview | 224 | AU (n=157) | Three potential triggers of the disease: (1) maladaptation to the social environment may act as a predisposing factor because 21% of patients mentioned interpersonal stress 8 weeks before uveitis; (2) influenza in 6.2%; (3) common cold in 3.6%. |
PU (n= 20) | |||||
Pan (n= 47) | |||||
Sen8 | 1971 | Personal interview | 48 | AU (n=36) | Stress was reported as a factor influencing the development or progression of uveitis by 37.5% of patients (16.6% reported stress in interpersonal relationships). |
PU (n=5) | |||||
Pan (n=7) | |||||
Kumar9 | 1981 | Modified Life Inventory Scale | 40 | Patients with controlled uveitis | Correlation between elevated stress scores and uveitis. |
Secchi et al10 | 1987 | Paykel Scale For Life Events (Paykel), Symptom Distress Checklist (Derogatis) | 60 | RAAU, (n=60; active n=15, quiescent n=45) | No difference between the uveitis group and a reference group concerning life events or psychological distress. |
Mayer et al11 | 1994 | Life Change Scale (Rahe) | 21 | AU (n=14) | Subjective importance of the patients' professional life on their flare-ups; psychological and social factors were perceived as triggers. |
IU (n=3) | |||||
PU (n=4) | |||||
Mulholland et al12 | 2000 | Holmes and Rahe's Social Readjustment Scale (Rahe), Spielberger State-Trait Anxiety Inventory (Spielberger) | 35 | Idiopathic RAAU (n=35) | Stress was not involved in triggering recurrences. |
Schiffman et al13 | 2001 | SF-36 Health survey (Ware), NEI VFQ-25 (Mangione) | 76 | AAU (n=13) | Scores significantly lower than those of the general US population; the severity of uveitis is correlated with a drop in scores. |
IU (n=17) | |||||
PU (n=26) | |||||
Pan (n=20) | |||||
Franke et al4 | 2004 | Schedule of Recent Experiences (Holmes), Stress Coping Questionnaire (Janke) Essen Coping Questionnaire (Franke), Brief Symptom Inventory (Derougatis), NEI VFQ (Mangione) | 51 | Chronic uveitis (n=51) | Patients with uveitis: more numerous recent life events, poorer coping strategies, greater psychological distress, poorer quality of life. At follow-up patients with recurrence of uveitis had poorer values than did those without recurrence. |
Carrim et al14 | 2006 | General Health Questionnaire (Goldberg), Social Readjustment Rating Questionnaire (Holmes) | 42 | AAU (n=42) | Relationship between stress and recurrence of AAU; poor general health during flare-up. |
AAU, acute anterior uveitis; AU, anterior uveitis; IU, intermediate uveitis; NEI VFQ, National Eye Institute visual functioning questionnaire; PU, posterior uveitis; Pan, panuveitis; RAAU, recurrent acute anterior uveitis.