Table 4

Previous studies on the psychopathology of uveitis

AuthorsYearQuestionnaires used (author)Number of uveitis patientsUveitis type, number of patientsResults
Schlaegel and Levitt51959Minnesota Multiphasic Personality Inventory49AU, AU+PU; granulomatous versus non-granulomatous; severity stagingSignificantly higher values of psychopathology in uveitis patients; the location, type and severity of uveitis or sex are not correlated with psycho-pathology.
Erbaugh and Fajardo61962Personal interview71No details givenUveitis patients report more depressive episodes prior to hospitalisation than controls.
Heaton71964Personal interview224AU (n=157)Three potential triggers of the disease: (1) maladaptation to the social environment may act as a predisposing factor because 21% of patients mentioned interpersonal stress 8 weeks before uveitis; (2) influenza in 6.2%; (3) common cold in 3.6%.
PU (n= 20)
Pan (n= 47)
Sen81971Personal interview48AU (n=36)Stress was reported as a factor influencing the development or progression of uveitis by 37.5% of patients (16.6% reported stress in interpersonal relationships).
PU (n=5)
Pan (n=7)
Kumar91981Modified Life Inventory Scale40Patients with controlled uveitisCorrelation between elevated stress scores and uveitis.
Secchi et al101987Paykel Scale For Life Events (Paykel), Symptom Distress Checklist (Derogatis)60RAAU, (n=60; active n=15, quiescent n=45)No difference between the uveitis group and a reference group concerning life events or psychological distress.
Mayer et al111994Life Change Scale (Rahe)21AU (n=14)Subjective importance of the patients' professional life on their flare-ups; psychological and social factors were perceived as triggers.
IU (n=3)
PU (n=4)
Mulholland et al122000Holmes and Rahe's Social Readjustment Scale (Rahe), Spielberger State-Trait Anxiety Inventory (Spielberger)35Idiopathic RAAU (n=35)Stress was not involved in triggering recurrences.
Schiffman et al132001SF-36 Health survey (Ware), NEI VFQ-25 (Mangione)76AAU (n=13)Scores significantly lower than those of the general US population; the severity of uveitis is correlated with a drop in scores.
IU (n=17)
PU (n=26)
Pan (n=20)
Franke et al42004Schedule of Recent Experiences (Holmes), Stress Coping Questionnaire (Janke) Essen Coping Questionnaire (Franke), Brief Symptom Inventory (Derougatis), NEI VFQ (Mangione)51Chronic uveitis (n=51)Patients with uveitis: more numerous recent life events, poorer coping strategies, greater psychological distress, poorer quality of life. At follow-up patients with recurrence of uveitis had poorer values than did those without recurrence.
Carrim et al142006General Health Questionnaire (Goldberg), Social Readjustment Rating Questionnaire (Holmes)42AAU (n=42)Relationship between stress and recurrence of AAU; poor general health during flare-up.
  • AAU, acute anterior uveitis; AU, anterior uveitis; IU, intermediate uveitis; NEI VFQ, National Eye Institute visual functioning questionnaire; PU, posterior uveitis; Pan, panuveitis; RAAU, recurrent acute anterior uveitis.