Measurements for contrast-loaded cerebrospinal fluid (CSF) in the intracranial subarachnoid space (SAS) and in the SAS of the optic nerve (ON) using cisternography and optic nerve sheath diameter in CT, L-PGDS concentration in the CSF of the SAS of the ON obtained during optic nerve sheath fenestration and during lumbar puncture (LP) as well as measurement of intracranial pressure (ICP) during LP
| Patient No | Age (years) | Dg | PE | Cisternography (HU) | CT | L-PGDS (mg/l) | ICP | ||||||
| M | F | side | IC SAS | ON SAS | ONSD (mm) | ON SAS | LP | LP | |||||
| Right | Left | Right | Left | Right | Left | (cmH2O) | |||||||
| 1 | 62 | IIH | Both | 489 | 101 | 29 | 8.40 | 7.10 | 69.7 | 39.3 | 18.1 | 25 | |
| 2 | 56 | IIH | Both | 557 | 52 | 112 | 9.49 | 9.62 | 70.8 | 32.2 | 33 | ||
| 3 | 48 | IIH | Both | 566 | 23 | 21 | 8.21 | 7.13 | 132.0 | 18.0 | 31 | ||
| 4 | 58 | IIH | Both | 541 | 25 | 33 | 7.80 | 7.70 | None | None | 47.0 | 36 | |
| 5 | 57 | BaM | Both | 557 | 11 | 71 | 8.45 | 10.92 | None | None | None | 25 | |
| 6 | 29 | IIH | Both | 428 | 111 | 98 | 7.62 | 7.24 | 76.3 | 47.8 | 17.0 | 30 | |
| 7 | 63 | IIH | Both | 529 | 8 | 96 | 8.30 | 7.70 | 170.0 | 13.1 | 61.6 | 48 | |
| 8 | 35 | CeA | Both | 716 | 161 | 198 | 8.17 | 7.92 | None | None | None | 28 | |
| 9 | 57 | IIH | Both | 448 | 47 | 82 | 7.20 | 6.40 | 85.8 | 72.3 | 24.4 | 50 | |
| 10 | 61 | IIH | Left | 539 | 20 | 26 | 6.00 | 9.70 | 0.2 | 32.3 | 25 | ||
| Mean±SD | 59.0±3.5 | 49.9±13.1 | 537.00±78.79 | 59.89±52.93 | 76.60±54.47 | 8.18±0.64 | 8.14±1.44 | 94.52±42.67 | 50.79±47.28 | 31.33±15.90 | 33.10±9.15 | ||
| Controls cisternography | |||||||||||||
| 1Ci | 81 | None | 347 | 212 | None | 38.5 | 17 | ||||||
| 2Ci | 45 | None | 851 | 1005 | 884 | 5.0 | 16.0 | 18 | |||||
| Mean±SD | 63.0±25.5 | 599.00±356.38 | 700.33±427.21 | 5.0 | 27.25±15.91 | 17.50±0.71 | |||||||
| Controls CT (ONSD) | |||||||||||||
| 1CT | 69 | None | 7.09 | 6.93 | |||||||||
| 2CT | 77 | None | 6.99 | 6.16 | |||||||||
| 3CT | 68 | None | 6.59 | 5.98 | |||||||||
| 4CT | 64 | None | 6.52 | 6.67 | |||||||||
| 5CT | 74 | None | 6.92 | 6.68 | |||||||||
| 6CT | 60 | None | 6.45 | 6.43 | |||||||||
| 7CT | 68 | None | 6.31 | 6.67 | |||||||||
| Mean±SD | 67.0±5.3 | 72.5±6.4 | 6.70±0.30 | 6.50±0.33 | |||||||||
Measurements of right ONs in italics for patient 10 are not included in the mean±SD calculations of right ONs, as this patient had papilloedema only on the left side.
BaM, history of bacterial meningitis; CeA, cerebellar astrocytoma;Ci, cisternography; CSF, cerebrospinal fluid; Dg, patient diagnoses; HU, Hounsfield units; IC, intracranial; ICP, intracranial pressure; IIH, idiopathic intracranial hypertension; L-PGDS, lipocalin-like prostaglandin D synthase; ONSD, optic nerve sheath diameter; PE, papilloedema.