Table 2

Overview of contrast box and optical coherence tomography measurements

ControlMultiple sclerosisGeneralised Estimating Equation
MeanSDMinMaxMeanSDMinMaxCI lowCI highp Value
Area under the curve Day2.0870.1111.8572.3191.9080.2151.0672.236−0.215−0.115<0.001
Area under the curve Night1.7920.2021.1082.1731.5860.3050.6502.185−0.263−0.100<0.001
Mean retinal nerve fibre layer thickness (μm)104.19.08312696.413.546133−11.7−3.6<0.001
Total macula volume (mm3)7.0710.3756.2938.0506.8380.4715.4557.674−0.357−0.0340.018
  • Differences between multiple sclerosis and healthy control eyes were analysed using Generalised Estimation Equations accounting for intersubject relations and correcting for age.