Meibomian gland parameters in healthy controls and glaucoma groups
| Group | Cell density of eyelid margin, cells/mm2 | Acinar unit | ||||||
|---|---|---|---|---|---|---|---|---|
| Superficial epithelium | Basal epithelium | Area, µm2±SD | Density, units/mm2 | Secretion reflectivity | Glandular orifice area, µm2±SD | MG wall: inhomogeneous appearance of MG wall | Periglandular interstice: inhomogeneous appearance of MG interstice | |
| Controls | 1810.27±234.19* | 4066.94±284.54*,** | 17020.49±7284.38** | 219.31±50.62** | 1.12±0.22** | 1894.44±336.65** | 1.33±0.37*** | 1.11±0.25*** |
| Group 1 | 1789.70±208.76 | 3930.64±264.0** | 16787.89±6311.04 | 195.33±58.55 | 1.23±0.30**** | 1847.66±818.42** | 1.63±0.50**** | 1.65±0.64**** |
| PF drugs | 1863.66±156.93 | 4030.83±121.66 | 17742.75±5131.74 | 222.40±45.25 | 1.08±0.13 | 1956.32±855.78 | 1.27±0.42***** | 1.31±0.32***** |
| Preserved drugs | 1752.84±157.07 | 3867.36±310.20 | 14953.24±6792.05****** | 174.98±59.53****** | 1.32±0.35 | 1779.03±809.91 | 1.85±0.42****** | 1.86±0.71****** |
| Group 2 | 1427.5±203.46 | 3548.58±467.08 | 12208.10±2771.18 | 100.47±33.23 | 2.49±0.46 | 2413.70±621.69 | 2.66±0.60 | 1.95±0.69 |
| Group 3 | 1380.46±169.44 | 3439.69±366.25 | 11652.55±2891.86 | 102.17±40.89 | 2.87±0.61 | 2332.03±339.77 | 3.17±0.53 | 2.73±0.66 |
*p<0.001 vs group 2; p<0.05 vs group 1, preserved drugs.
**p<0.05 vs groups 2 and 3; p<0.001 for secretion reflectivity.
***p<0.05 vs groups 1, 2 and 3.
****p<0.05 vs groups 2 and 3.
*****p<0.05 vs preserved drugs.
******p<0.05 vs groups 2 and 3.
MG, Meibomian gland; PF, preservative free.