Comparison of macular and circumpapillary RNFL thickness measurement for glaucoma detection using OCT
| Authors | OCT device | Main finding |
|---|---|---|
| Wollstein et al1 | Prototype OCT | RNFL thickness had higher sensitivity and specificity for the detection of visual field abnormalities than macular thickness |
| Leung et al6 | Stratus OCT | RNFL thickness outperformed both total macular and macular nerve fibre layer thickness in terms of glaucoma detection and visual function correlation |
| Medeiros et al7 | Stratus OCT | The RNFL parameter inferior thickness was significantly better than the macular thickness parameter |
| Na et al22 | Cirrus OCT | RNFL thickness measurements were generally superior to those of macular thickness |
| Seong et al27 | RTVue OCT | Macular inner retinal thickness showed glaucoma discrimination ability comparable to that of RNFL thickness in patients with early visual field defects |
| In eyes with advanced or peripheral defect, RNFL measurement showed a better glaucoma diagnostic ability than did macular inner retinal layer measurement | ||
| Huang et al20 | RTVue OCT | Average RNFL thickness is the optimal individual OCT parameter to detect perimetric glaucoma |
| Simultaneous evaluation on disc morphology, RNFL and macular inner retinal thickness can improve the diagnostic accuracy in diagnosing glaucoma | ||
| Nakatani et al19 | Topcon 3D OCT | For the diagnosis of early glaucoma, macular parameters had high discriminating power and high reproducibility comparable with RNFL parameters |
OCT, optical coherence tomography; RNFL, retinal nerve fibre layer; 3D, three dimensional.