Clinical characteristics
| OSDI score | BUT | STI | Corneal staining | Meibo score | Meibum score | |
|---|---|---|---|---|---|---|
| Controls | 9.5±4.8* | 12.0±2.1* | 18.0±5.0* | 0.3±1.1* | 0.12±0.03* | 1.30±0.72* |
| Group 1 | 16.4±5.4** | 7.2±1.9** | 9.3±5.1** | 1.9±2.3 | 0.48±0.32 | 2.05±0.91 |
| PF drugs | 9.4±3.5*** | 7.7±1.8**** | 9.1±3.1**** | 1.9±2.2 | 0.44±0.41 | 1.98±0.68 |
| Preserved drugs | 18.7±4.1**** | 6.1±1.9**** | 9.4±6.1**** | 1.9±1.8 | 0.53±0.44 | 2.12±1.03 |
| Group 2 | 30.8±6.7 | 4.1±1.5 | 7.2±2.7 | 2.3±2.1 | 0.54±0.38 | 2.23±1.15 |
| Group 3 | 32.6±7.2 | 3.9±1.5 | 6.8±2.7 | 2.2±1.9 | 0.57±0.63 | 2.21±1.23 |
*p<0.05 vs groups 1, 2 and 3.
**p<0.05 vs groups 2 and 3.
***p<0.05 vs group 1 preserved drugs and vs groups 2 and 3.
****p<0.05 vs groups 2 and 3.
BUT, break-up time; OSDI, Ocular Surface Disease Index; PF, preservative free; STI, Schirmer test I.