Conjunctival hyperaemia score (worse eye) at each visit—safety set
| T2345 (N=213) | BPL (N=189) | Difference between groups† | |||||
|---|---|---|---|---|---|---|---|
| Hyperaemia score* | Hyperaemia score* | ||||||
| Visit | 2 | 3–4 | 5–6 | 2 | 3–4 | 5–6 | |
| D0 | 36 (17.0) | 15 (7.0) | 1 (0.5) | 38 (20.1) | 5 (2.6) | – | ND |
| D15 | 42 (20.1) | 15 (7.1) | – | 50 (26.9) | 11 (5.9) | – | p=0.181 |
| D42 | 31 (14.9) | 11 (5.3) | – | 41 (22.0) | 16 (8.6) | – | p=0.003 |
| D84 | 34 (16.5) | 10 (4.9) | – | 40 (21.5) | 14 (7.6) | – | p=0.019 |
Data are number of patients (%). Value shown in bold: p<0.05. ND=not determined.
*The severity of conjunctival hyperaemia was scored using a photographic scale derived from the McMonnies score (2=mild, 3–4=moderate, 5–6=severe).
†Cochran-Mantel-Haenszel stratified by country.
BPL, benzalkonium chloride-preserved latanoprost.