Table 4

Visual outcomes following intraophthalmic artery melphalan for retinoblastoma: summary of visual acuity results

FeatureNumber (%)
n=12
Age appropriate visual acuity before IAM
 Normal12 (100%)
 Below normal0 (0%)
Age appropriate final visual acuity after IAM 
 Normal7 (58%)
 Below normal5 (42%)
 Eyes with any reduction of visual acuity5 (42%)
 Eyes losing greater than 6 Snellen lines2 (17%)
Any visual loss in relation to tumour quadrant relative to optic disc
 Superior0/2
 Nasal0/2
 Temporal4/6
 Inferior1/2
Any visual loss in relation to tumour distance to fovea
 0–0.2 mm1/3
 0.2–0.5 mm1/2
 0.5–1.0 mm1/1
 1.0–1.5 mm0
 1.5–3.0 mm0/2
 >3.0 mm2/4
Reason for visual loss 
Choroidal Ischaemia 
 Diffuse2 (40%)
 Sectoral2 (40%)
Retinal detachment 
 Diffuse1 (20%)
 Sectoral0 (0%)
  • IAM, intra-arterial melphalan.