Comparison of radiation, surgical and laser treatment modalities
| Modality | No. of studies included | Weighted mean rate of local failure (%) | Weighted mean tumour LBD (mm) | Weighted mean tumour height (mm) | No. of pts. included |
|---|---|---|---|---|---|
| Radiation (n=11435) | |||||
| Iodine-125 brachytherapy | 13 | 9.60 | 11.10 | 4.80 | 2104 |
| Ruthenium-106 brachytherapy | 7 | 9.60 | 10.90 | 4.10 | 1653 |
| Palladium-103 brachytherapy | 1 | 4.00 | 10.30 | 3.90 | 100 |
| Cesium-131 brachytherapy | 1 | 9.00 | 12.60 | 5.40 | 11 |
| Gamma knife radiosurgery | 4 | 9.50 | N/A | 7.70 | 262 |
| Fractionated radiotherapy | 2 | 6.20 | 11.40 | 4.60 | 262 |
| Proton beam radiation therapy | 7 | 4.20 | 14.00 | 5.50 | 6825 |
| Helium ion radiation therapy | 1 | 4.60 | 11.90 | 6.70 | 218 |
| Weighted average | 6.15 | 12.90 | 5.21 | ||
| Surgical (n=537) | |||||
| Endoresection | 3 | 4.60 | 9.60 | 7.90 | 86 |
| Trans-scleral resection | 2 | 21.3 | 13.60 | 8.00 | 451 |
| Weighted average | 18.6 | 12.96 | 7.98 | ||
| Laser (n=552) | |||||
| Transpupillary thermotherapy | 7 | 20.80 | 7.00 | 2.50 | 552 |
| Weighted average | 20.80 | 7.00 | 2.50 | ||
LBD, largest basal diameter; No., number; Pts., patients.