Table 1

Definitions of TNM for eyelid carcinoma, AJCC Cancer Staging Manual, Seventh Edition8

Primary tumour (T)
 TXPrimary tumour cannot be assessed
 T0No evidence of primary tumour
 TisCarcinoma in situ
 T1Tumour ≤5 mm in greatest dimension; not invading tarsal plate or eyelid margin
 T2aTumour >5 mm, but not >10 mm, in greatest dimension; or, any tumour that invades the tarsal plate or eyelid margin
 T2bTumour >10 mm, but not >20 mm, in greatest dimension; or, involves full thickness eyelid
 T3aTumour >20 mm in greatest dimension; or, any tumour that invades adjacent ocular or orbital structures; any T with perineural invasion
 T3bComplete tumour resection requires enucleation, exenteration or bone resection
 T4Tumour is not resectable because of extensive invasion of ocular, orbital or craniofacial structures, or brain
Regional lymph nodes (N)
 NXRegional lymph nodes cannot be assessed
 cN0*No regional lymph node metastasis, based on clinical evaluation or imaging
 pN0†No regional lymph node metastasis, based on lymph node biopsy
Distant metastasis (M)
 M0No distant metastasis
 M1Distant metastasis
  • *Clinical N0.

  • †Pathological N0.

  • AJCC, American Joint Committee on Cancer.