Baseline features of uveal metastases related to four most prevalent primary cancer sites
| Primary site of tumour | ||||
|---|---|---|---|---|
| Breast | Lung | Oesophagus | Prostate | |
| Patients | 41 | 27 | 8 | 5 |
| Eyes | 49 | 31 | 9 | 5 |
| Age (mean) years | 57.1 SD:12.4 Range: 33–86 | 63.1 SD: 14.9 Range: 21–85 | 67 SD: 4.7 Range: 62–72 | 58 SD:12.4 Range: 36–76 |
| Gender | ||||
| Male | 1 | 21 | 7 | 5 |
| Female | 40 | 6 | 1 | 0 |
| Concurrent metastasis (n of cases %) | 22 (53.7) | 7 (25.9) | 3 (37.5) | 4 (80) |
| UM was the first sign of primary cancer in (n of cases %) | 6 (14.6) | 16 (59.3) | 1 (12.5) | 0 |
| Mean time interval between detection of primary cancer and UM (months) | 57.9 (median: 24, SD: 76, Range: 1–288) | 23.1 (median: 12, SD:26.5, Range: 1–120) | 32.5 (median: 12, SD: 29.1, Range: 12–84) | 78 (median: 78, SD: 37.3, Range: 36–120) |
| Laterality (n of cases) | ||||
| Unilateral | 33 | 23 | 7 | 5 |
| Bilateral | 8 | 4 | 1 | 0 |
| Mean largest tumour diameter | 13.2 mm SD:4 Range: 3.2–21.7 mm | 12.6 mm SD: 5.9 Range: 2.7–22.2 | 11 mm SD: 4.3 Range: 1.9–17 mm | 17.5 mm SD: 2 Range 15.5 to 20.6 |
| Mean tumour thickness | 2.8 mm SD: 2.2 Range: 0.6–13 | 4.1 mm SD:3.2 Range: 1.2–14.2 | 3.1 mm SD:1.8 Range: 0.9 to 6.8 | 5 mm SD: 3.6 Range: 2.7–11.2 |
| Exudative retinal detachment (RD) (n of eyes %) | 15 (36.5) | 5 (18.5) | 2 (25) | 3 (60) |
| Mean baseline VA | 6/30 0.7 log MAR SD: 0.7 | 6/24 0.6 log MAR SD: 0.6 | 6/48 0.9 log MAR SD: 0.7 | 6/30 0.7 log MAR SD: 0.8 |
| Localisation of UM (n of eyes) | ||||
| Iris | 3 | 4 | 1 | 0 |
| Ciliary body | 1 | 2 | 0 | 0 |
| Choroid | 45 | 21 | 8 | 5 |
VA, visual acuity.