Table 3

Mean and SD in parenthesis of Hb's percentage analysing optic disc photographs with Laguna ONhE (optic nerve hemoglobin) program of MS patients with previous ON attack and without history of previous attack, and statistical significance (p)

MS patients without ON (n=26)MS patients with ON (n=12)p Value*
Average Hb59.67 (10.11)56.55 (11.26)0.013
Hb 169.88 (15.98)69.56 (17.09)0.205
Hb 268.24 (14.66)68.02 (15.32)0.025
Hb 363.09 (12.01)60.23 (12.89)0.027
Hb 467.23 (15.77)67.04 (16.66)0.321
Hb 569.40 (13.01)67.99 (13.89)0.112
Hb 662.94 (12.21)60.51 (13.50)0.066
Hb 759.62 (15.98)59.01 (16.54)0.135
Hb 864.10 (14.10)60.22 (15.01)0.014
Hb 963.45 (10.55)61.41 (12.28)0.035
Hb 1051.59 (18.88)48.11 (19.71)0.030
Hb 1152.65 (16.32)48.89 (16.66)0.004
Hb 1254.02 (13.56)49.00 (13.99)0.005
Hb 1347.99 (19.67)45.89 (21.79)0.026
Hb 1447.18 (17.00)45.87 (18.29)<0.001
Hb 1548.33 (12.98)46.75 (13.82)0.003
Hb 1653.72 (20.19)52.95 (21.83)0.043
Hb 1756.77 (17.56)54.86 (17.02)0.005
Hb 1859.06 (13.45)56.11 (13.94)0.004
Hb 1963.77 (21.87)62.67 (23.01)0.087
Hb 2069.59 (15.19)67.28 (15.98)0.021
Hb 2169.97 (14.08)67.70 (12.89)0.024
Hb 2271.88 (18.23)70.00 (19.99)0.225
Hb 2374.83 (15.76)73.61 (15.05)0.056
Hb 2470.05 (12.01)68.95 (12.32)0.012
  • *Significant difference (p<0.05) in Mann–Whitney U test between MS without ON and MS patients with ON.

  • Hb, haemoglobin; MS, multiple sclerosis; ON, optic neuritis.