Outcome of intracameral r-tPA injection in 40 patients with refractory fibrin reaction
| Parameter | Pre-r-tPA injection | 1 day after r-tPA injection | p Value | 1 week after r-tPA injection | p Value | 1 month after r-tPA injection | p Value |
|---|---|---|---|---|---|---|---|
| Fibrin in AC, n (%) | 40 (100%) | 8 (20%) | <0.0001 | 9 (23.7%) | <0.0001 | 2 (5.3%) | <0.0001 |
| BCVA (logMAR) (including other pathology) (n=40) | 0.61±0.38 | 0.67±0.41 | 0.50 | 0.47±0.37 | 0.10 | 0.45±0.37 | 0.06 |
| BCVA (logMAR) with no other pathology (n=32) | 0.56±0.36 | 0.6±0.37 | 0.66 | 0.41±0.35 | 0.09 | 0.36±0.3 | 0.02 |
| Endothelial cell count (n=6) cells/mm2, mean±SD | 1830±589 | 1891±723 | |||||
| IOP (mmHg), mean±SD | 13±2.9 | 12.2±3.1 | 0.23 | 13.7±3.2 | 0.31 | 13.9±3.2 | 0.19 |
| CME, n (%) | 5 (12.5%) |
AC, anterior chamber; BCVA, best-corrected visual acuity; CME, cystoid macular oedema; IOP, intraocular pressure; r-tPA, recombinant tissue plasminogen activator.