Table 2

Treatment comparison of responders, intent-to-treat population*

Responders (%)*
Time pointBimatoprost
/timolol PF
Bimatoprost/timololTreatment difference
(95% CI)†
p Value‡
8:0090.6%
(252/278)
89.8%
(254/283)
0.9% (–4.0% to 5.8%) 0.722
10:0086.3%
(240/278)
85.5%
(242/283)
0.8% (–4.9% to 6.6%) 0.780
16:0087.1%
(242/278)
83.4%
(236/283)
3.7% (–2.2% to 9.5%) 0.222
  • *Responders are defined as patients with a ≥20% reduction from baseline in worse eye IOP at week 12. Worse eye is the eye with the higher mean diurnal IOP at baseline.

  • †95% CI of treatment differences was constructed using the normal approximation for the binomial distribution.

  • ‡Pearson's χ2 test of the equality of proportions between treatment groups.

  • IOP, intraocular pressure; PF, preservative-free.