Incidence of flow index reduction in the healthy control (HC) and multiple sclerosis subgroups
| Groups (n eyes) | ONH flow index (%) | Parafoveal flow index (%) | ||||
|---|---|---|---|---|---|---|
| Within normal (>5%) | Borderline (1–5%) | Abnormal (<1%) | Within normal (>5%) | Borderline (1–5%) | Abnormal (<1%) | |
| HC (n=21) | 20 (95) | 0 | 1 (5) | 21 (100) | 0 | 0 |
| MS total (n=52) | 36 (69) | 2 (4) | 14 (27) | 48 (92) | 2 (4) | 2 (4) |
| MS –ON (n=38) | 29 (76) | 1 (3) | 8 (21) | 34 (90) | 2 (5) | 2 (5) |
| MS + ON (n=14) | 7 (50)* | 1 (7) | 6 (43)* | 14 (100) | 0 | 0 |
The cutoff points of 1st and 5th percentiles were set at 2.33 and 1.65 SDs below the mean, respectively, according to normal distribution.
*Significantly different from the HC group at the p<0.05 level using Fisher's exact test.
MS, multiple sclerosis; ONH, optic nerve head.