Outcomes and complications comparing DSAEK with ACIOL and PCIOL over 1 year and 3 years of follow-up
| Outcomes and complications | ACIOL (n=18) | PCIOL (n=114) | p Value |
|---|---|---|---|
| Outcomes (1 year) | |||
| *Postoperative ECD (mean ±SD) | 1910 (615) | 2132 (609) | 0.618 |
| †Number of graft failure at 1 year (%) | 0 (0.0) | 3 (2.6) | 0.486 |
| Postoperative visual acuity | |||
| Overall (logMAR; mean ±SD) | 0.7 (0.7) | 0.6 (1.1) | 0.630 |
| ‡Outcomes (3 years) | |||
| Postoperative ECD (mean ±SD) | 1236 (762) | 1906 (587) | 0.022 |
| Number of graft failures at 3 years (%) | 7 (36.8) | 12 (10.3) | 0.006 |
| §Complications | |||
| Glaucoma | 8 (44.4) | 20 (17.5) | 0.009 |
| Graft rejection episode | 0 (0) | 2 (1.8) | 0.644 |
| Graft detachment | 0 (0) | 1 (0.9) | 0.745 |
| Corneal infection | 0 (0) | 2 (1.8) | 0.644 |
| Epitheliopathy | 0 (0) | 2 (1.8) | 0.644 |
| Primary graft failure | 0 (0) | 1 (0.9) | 0.745 |
| Recurrence of primary disease | 0 (0) | 0 (0) | NA |
| Viral/herpetic infection | 0 (0) | 0 (0) | NA |
| Suprachoroidal haemorrhage | 0 (0) | 0 (0) | NA |
| Endophthalmitis | 0 (0) | 0 (0) | NA |
*Number of patients with valid endothelial cell density (ACIOL, n=14; PCIOL, n=101).
†Graft failure was defined as irreversible loss of optical clarity, sufficient to compromise vision for a minimum of three consecutive months.
‡Number of patients (ACIOL, n=8; PCIOL, n=39).
§Complications as recorded in our prospective SCTS database at 1 year follow-up.
ACIOL, anterior chamber intraocular lens; DSAEK, Descemet's stripping automated endothelial keratoplasty; ECD, endothelial cell density; logMAR, logarithm of the minimum angle of resolution; NA, not applicable; PCIOL, posterior chamber intraocular lens; SCTS, Singapore Corneal Transplant Study.