Characteristics of the study groups
| Group (patients/eyes) | |||
|---|---|---|---|
| HC (21/21) | MS −ON (25/38) | MS +ON (10/14) | |
| Age (yrs) | 50±9.6 | 47±12.7 | 40±8.9 |
| High-contrast LogMAR BCVA | 0.01±0.1 | 0.04±0.1 | 0.01±0.1 |
| Low-contrast LogMAR BCVA | none | 0.65±0.2 | 0.72±0.2 |
| EDSS | n/a | 3.8±1.7 | 3.2±1.9 |
| EDMUS | n/a | 2.5±2.0 | 3.0±2.0 |
| IOP (mm Hg) | 15±2.3 | 15±3.1 | 14±2.2 |
| MS duration (yrs) | n/a | 12±8.4 | 17±10.4 |
BCVA, best corrected visual acuity; EDMUS, European Database for Multiple Sclerosis Grading Scale; EDSS, Expanded Disability Status Scale; HC, healthy control; IOP, intraocular pressure; MAR, minimum angle of resolution; MS, multiple sclerosis; MS+ON, MS with history of ON; MS−ON, MS without history of ON; n/a, not applicable; ON, optic neuritis.