Table 1

Baseline characteristics of subjects with early age-related macular degeneration

CharacteristicPlacebo (n=28)10 mg lutein (n=26)20 mg lutein (n=27)lutein +zeaxanthin (n=27)
Age (years)69.0±7.569.7±8.369.3±6.968.5±6.9
Sex (male/female)11/179/1714/1312/15
Education (years)12.2±2.810.8±2.712.2±2.910.5±4.1
BMI (kg/m2)24.8±3.024.1±3.425.1±3.324.6±3.6
Waist circumference (cm)27.10±7.6127.86±7.2528.64±5.9327.92±7.19
Serum lipids (mmol/L)
 Total cholesterol5.02±1.764.98±1.075.09±0.885.25±0.95
 Triglyceride1.57±1.581.54±0.681.49±0.821.78±0.79
 HDL-cholesterol1.39±0.441.39±0.321.41±0.261.48±0.29
 LDL-cholesterol3.09±0.613.19±0.753.2±0.613.34±0.61
Smoking (%)
 Never89.384.688.985.2
 Former3.611.57.43.7
 Current7.13.83.711.1
Early cataracts (%)*21.423.018.529.6
  • There were no significant between-group differences in any baseline demographic or clinical variable.

  • For continuous variables, all values are mean±SD. Comparisons among groups were carried out using analysis of variance for continuous variables or the χ2 test for categorical variables.

  • *Cataracts diagnosed and graded according to the Lens Opacities Classification System III.

  • BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein.