Comparison of baseline clinical and microbiological parameters between the patients recruited in the voriconazole and natamycin groups
| Parameters | Voriconazole (n=58) | Natamycin (n=60) | p Value |
|---|---|---|---|
| Mean age (years) | 42 (32.25 to 54.75) | 40 (28.75 to 51) | 0.22 |
| Men | 43/58 | 42/60 | 0.77 |
| Women | 15/58 | 18/60 | 0.77 |
| Mean corneal infiltrate size* (day 1) | 2.619 (2 to 3.76) | 2.75 (2 to 3.6) | 0.86 |
| Mean corneal epithelial defect size* | 2.5±1.37 | 2.77±2.8 | 0.98 |
| Presenting visual acuity (logMAR) | 0.9 (0.3 to 2) | 0.6 (0.3 to 1.5) | 0.20 |
| Aspergillus sp. in culture | 7/58 | 8/60 | 1.0 |
| Fusarium sp. in culture | 13/58 | 16/60 | 0.74 |
| No growth in culture | 14/58 | 14/60 | 1.0 |
| Other species in culture | 24/58 | 22/60 | 0.73 |
Corneal scraping was positive for septate fungal filaments in all 118 patients.
*Mean of length plus width of ulcer in millimetre.
logMAR, logarithm of the minimum angle of resolution.