The presence of reticular drusen (RDR) at baseline and the appearance of the characteristic RDR pattern (confocal scanning laser ophthalmoscopy: dot, target, ribbon; spectral-domain optical coherence tomography (SD-OCT): waves, spikes) in different imaging modalities
| Study eyes: 98 eyes of 98 patients | IR | BR | FAG | FAF | Colour | SD-OCT | At least one modality |
|---|---|---|---|---|---|---|---|
| Presence of RDR at baseline | 43 (43.9%) κ=0.96 | 25 (25.5%) κ=0.73 | 27 (27.6%) κ=0.61 | 41 (41.8%) κ=0.88 | 24 (24.5%) κ=0.58 | 38 (38.8%) κ=0.89 | 43 (43.9%) κ=0.96 |
| Dot | 43 (100%) κ=0.96 | 22 (88.0%) κ=0.54 | 26 (96.3%) κ=0.59 | 40 (97.6%) κ=0.74 | 21 (87.5%) κ=0.54 | waves: 38 (100%) κ=0.95 | 43 (100%) κ=0.96 |
| Ribbon | 0 (0%) κ=1 | 8 (32.0%) κ=0.67 | 3 (11.1%) κ=0.57 | 11 (26.9%) κ=0.78 | 10 (41.7%) κ=0.56 | 12 (27.9%) κ=0.75 | |
| Target | 35 (81.4%) κ=0.87 | 19 (76.0%) κ=0.65 | 0 (0%) κ=1 | 20 (48.8%) κ=0.57 | 0 (0%) κ=1 | spikes: 34 (89.5%) κ=0.77 | 36 (83.7%) κ=0.85 |
| AREDS 3 (23 eyes) | 10 (43.5%) | 6 (26.1%) | 7 (30.4%) | 9 (39.1%) | 5 (21.8%) | 9 (39.1%) | 10 (43.5%) |
| AREDS 4 (75 eyes) | 33 (44.0%) | 19 (25.3%) | 20 (26.7%) | 32 (42.7%) | 19 (25.3%) | 29 (38.7%) | 33 (44.0%) |
The absolute number, the percentage and the κ value are given, respectively. In addition, results for AREDS 3 and AREDS 4 subjects are separated.
AREDS, age-related eye disease study; BR, blue reflectance; FAF, fundus autofluorescence; FAG, fluorescein angiography; IR, infrared reflectance.