Table 1

Comparison of various laser trabeculoplasties

Wavelength532 nm532, 577 or 810 nm790 nm532 or 577 nm
Spot size400 µm200–300 µm200 µm100 µm
Pulse duration3×10−9 s200–300×10−3 s
15% duty cycle
5–10×10−3 s5–10×10−3 s
Energy or power per pulse0.6–1.2 mJ1000–2000 mW30–50 mJ500–1000 mW
MechanismSelective destruction of pigmented trabecular meshwork cells without thermal or collateral damageThermal effects without trabecular meshwork damage in repetitive microsecond pulses followed by intermittent rest periodNear-infrared energy with deeper penetration into the juxtacanalicular meshwork and the inner wall of Schlemm's canalSequence of pattern laser spots on the trabecular meshwork without overlapping, much shorter pulse durations with more spots for the same area to reduce thermal injury diffusion distance
Recommended number of applications50 or 100 confluent spots60–100 spots or confluent spots50 adjacent, non-overlapping laser spots8 or 16 segments
Recommended extent of trabecular meshwork treatment180° or 360° of trabecular meshwork180° or 360° of trabecular meshwork180° of trabecular meshwork180° or 360° of trabecular meshwork
Expected endpointSmall bubblesNo visible tissue reactionMini-bubble or burst of pigmentsNo visible tissue reaction after energy titration
RepeatableYesYesYes (theoretically)Unknown
Common complicationsIOP spikes and anterior uveitisBurning or heat sensation. IOP spikes and anterior uveitis are uncommonIOP spikes are possibleTransient IOP spikes are possible
  • IOP, intraocular pressure; MLT, micropulse laser trabeculoplasty; PLT, pattern scanning trabeculoplasty; SLT, selective laser trabeculoplasty; TSLT, titanium-sapphire laser trabeculoplasty.