Characteristic | Bimatoprost PF (N=302) | Bimatoprost (N=295) |
---|---|---|
Age, years, mean (range) | 64.6 (29–91) | 65.0 (29–92) |
Gender, male, n (%) | 132 (43.7) | 114 (38.6) |
Race, n (%) | ||
Caucasian | 219 (72.5) | 206 (69.8) |
Black | 48 (15.9) | 55 (18.6) |
Hispanic | 29 (9.6) | 27 (9.2) |
Asian | 4 (1.3) | 5 (1.7) |
Other | 2 (0.7) | 2 (0.7) |
Glaucoma medications requiring washout* | ||
All medications, n (%) | 235 (77.8) | 222 (75.3) |
Prostaglandin agonists, n (%)† | 195 (64.6) | 169 (57.3) |
Latanoprost | 103 (34.1) | 87 (29.5) |
Bimatoprost | 44 (14.6) | 42 (14.2) |
Travoprost | 48 (15.9) | 42 (14.2) |
Iris colour, n (%) | ||
Dark | 187 (61.9) | 187 (63.4) |
Brown | 118 (39.1) | 113 (38.3) |
Dark brown | 43 (14.2) | 40 (13.6) |
Blue/grey-brown | 10 (3.3) | 19 (6.4) |
Green-brown | 15 (5.0) | 12 (4.1) |
Other dark | 1 (0.3) | 3 (1.0) |
Light | 114 (37.7) | 107 (36.3) |
Blue | 55 (18.2) | 48 (16.3) |
Blue-grey | 13 (4.3) | 17 (5.8) |
Grey | 2 (0.7) | 1 (0.3) |
Green | 12 (4.0) | 10 (3.4) |
Hazel | 31 (10.3) | 28 (9.5) |
Other light | 1 (0.3) | 3 (1.0) |
Dark/light‡ | 1 (0.3) | 1 (0.3) |
Diagnosis (both eyes), n (%) | ||
OHT | 105 (34.8) | 98 (33.2) |
Glaucoma | 197 (65.2) | 195 (66.1) |
OHT/glaucoma§ | 0 (0.0) | 2 (0.7) |
Mean IOP±SD, mm Hg, average of both eyes | ||
8:00 | 24.53±2.20 | 24.46±2.02 |
10:00 | 23.30±2.85 | 23.26±2.61 |
16:00 | 22.31±2.97 | 22.29±3.11 |
Baseline mean corneal thickness (worse eye), μm | 554.76 | 554.46 |
*Other than prostaglandin analogues, IOP-lowering medications requiring washout included α-agonists, carbonic anhydrase inhibitors, β-adrenergic blocking agents and combination products.
†For latanoprost, bimatoprost and travoprost, based on total number of patients receiving prostaglandin agonists.
‡One eye colour dark and one eye colour light.
§Patient with OHT in one eye and glaucoma in the other.
IOP, intraocular pressure; OHT, ocular hypertension; PF, preservative-free.