Details of patients with non-resolving microbial keratitis showing both precollagen and postcollagen crosslinking parameters
| Age/gender | Clinical diagnosis | Microbiology reports | Depth of infiltrate | Hypopyon | Post-CXL response | Time for epithelial healing | Time for resolution of infiltrate | Time for resolution of hypopyon |
|---|---|---|---|---|---|---|---|---|
| 36/M | G +ve | Staph. | Superficial stroma | No | Healed with scar | 14 days | 4 weeks | No hypopyon |
| 42/M | G −ve | Pseudomonas | Full thickness ring infiltrate | 5 mm | Non-resolving; increase in hypopyon | – | – | Non-resolving |
| 68/F | G +ve | Staph. | Surface infiltrate | No | Healed with scar | 18 days | 4 weeks | No hypopyon |
| 52/M | G +ve | Strepto. | Full thickness | 4 mm | Non-resolving | – | – | Non-resolving |
| 47/M | G +ve | Staph. | Superficial stromal | No | Healed with scar | 15 days | 4 weeks | No hypopyon |
| 65/M | G −ve | Pseudomonas | Anterior stroma | No | Healed with scar; hypopyon | 28 days | 5 weeks | 7 weeks |
| 71/F | G +ve | Staph. | Anterior third of stroma | No | Healed with scar | 21 days | 5 weeks | – |
| 36/M | G −ve | Inconclusive | Full thickness | 3 mm | Non-resolving; increase in hypopyon | – | – | Non-resolving |
| 53/M | G +ve | Staph. | Superficial stromal | No | Healed with scar | 14 days | 4 weeks | No hypopyon |
| 27/F | Fungal | Aspergillus | Anterior third of stroma | 5 mm | Healed with scar Increase in hypopyon | 26 days | 6 weeks | 8 weeks |
| 58/M | Fungal | Candida | Deep stromal and endothelial plaque | 2 mm | Non-resolving | – | – | Non-resolving |
| 65/F | Fungal | Fusarium | Superficial + mid-deep stroma | No | Partial scar; non-resolving; hypopyon | – | Only the superficial infiltrate resolved in 5 weeks | Non-resolving |
| 43/M | Fungal | Aspergillus | Anterior stroma | 1 mm | Healed with scar; increase in hypopyon | 28 days | 6 weeks | 8 weeks |
| 54/F | Fungal | Candida | Deep stroma | 2 mm | Non-resolving | – | – | Non-resolving |
| 48/M | Fungal | Aspergillus | Anterior third stroma | No | Healed with scar; hypopyon | 28 days | 5 weeks | 6 weeks |
G +ve- Gram positive; G -ve- Gram negative; Staph.- Staphylococci species; Strepto.- Streptococci species.