Table 1

Intraocular pressure (IOP) and medication outcomes following Trabectome

First author	Type of study	Total n	Mean baseline IOP (mm Hg)	Mean final IOP (mm Hg)	% IOP decrease	Mean # decrease in medication	Length of study (months)
Standalone Trabectome outcomes
POAG of Ting13	Prospective	450	26	17	34	0.57	12
PXG of Ting13	Prospective	67	29	16	44	0.88	12
Jea14	Retrospective	115	28	17	41	1	30
Minckler15	Prospective	1151	26	17	36	1.7	60
Ahuja16	Retrospective	88	26	13	50	0.3	48
Maeda17	Prospective	80	27	18	33	1.7	12
Werth18	Prospective	92	20	15	23	Not reported	12
Combined phacoemulsification with Trabectome outcomes
Francis19	Prospective	304	20	17	17	1.22	21
POAG of Ting13	Prospective	263	20	16	22	0.75	12
PXG of Ting13	Prospective	45	22	14	35	0.96	12
Minckler15	Prospective	681	20	16	21	0.87	36
Francis20	Prospective	89	22	15	30	1	12
Ahuja16	Retrospective	158	19	12	39	0.5	45
Klamann21	Retrospective	27	23	14	40	0.29	12
Klamann12	Retrospective	74	21	13	37.5	0.12	6
Francis22	Prospective	114	22	15	31	1	24
Werth18	Prospective	30	21	19	21	Not reported	12

From table 1, it can be seen that AIT can be expected to lower the IOP by approximately 36% to a final average IOP around 16 mm Hg. The overall mean baseline IOP for AIT was 26.71±1.34 mm Hg and decreased by 10.5±1.9 mm Hg (39% decrease) on 0.99±0.54 fewer medications. For phaco-AIT, the mean baseline IOP of 21±1.31 mm Hg decreased by 6.24±1.98 mm Hg (27% decrease) on 0.76±0.35 fewer medications.
AIT, ab-interno trabeculectomy; IOP, intraocular pressure; POAG, paediatric open-angle glaucoma; PXG, pseudoexfoliation glaucoma.