Results of univariate regression analyses of the clinical variables associated with the rate of endothelial cell loss
| B | 95% CI | p Value | |
|---|---|---|---|
| Age at surgery (years) | −0.048 | −0.165 to 0.069 | 0.420 |
| Sex (male) | −0.882 | −4.072 to 2.308 | 0.590 |
| Eye (right) | 0.284 | −2.646 to 3.214 | 0.850 |
| Diabetes mellitus | −1.514 | −4.554 to 1.526 | 0.332 |
| Hypertension | −0.770 | −4.030 to 2.490 | 0.645 |
| Uveitis | −0.036 | −3.746 to 3.674 | 0.985 |
| Presence of AGV implant | −6.895 | −9.795 to −3.995 | <0.001 |
| No. of previous ocular interventions | −1.528 | −3.098 to 0.042 | 0.159 |
| Intraocular pressure (mm Hg) | −0.002 | −0.004 to 0.000 | 0.180 |
| No. of glaucoma medications | 0.001 | −0.040 to 0.042 | 0.945 |
| Best-corrected visual acuity (logMAR) | 0.318 | −3.322 to 3.958 | 0.865 |
| Glaucoma type | |||
| Neovascular glaucoma | 0.906 | −2.094 to 3.905 | 0.549 |
| Secondary glaucoma | 0.925 | −1.977 to 3.827 | 0.548 |
| Primary open-angle glaucoma | −1.077 | −2.397 to 0.243 | 0.126 |
| Primary angle-closure glaucoma | −0.946 | −4.356 to 2.464 | 0.799 |
| Corneal specular microscopy | |||
| Cell density (cells/mm2) | 0.015 | −3.750 to 3.765 | 0.992 |
| Hexagonality (%) | 0.070 | −0.065 to 0.205 | 0.308 |
| Coefficient of variation of cell area (%) | −0.005 | −0.197 to 0.187 | 0.956 |
In this analysis, 72 patients with an AGV implantation and 31 controls without an AGV were enrolled. Rate of endothelial cell loss indicates decrease in endothelial cell density per year (%).
AGV, Ahmed glaucoma valve; B, regression coefficient; logMAR, logarithm of the minimum angle of resolution.