Baseline characteristics of quartiles based on baseline gap between standard and LLVA from the HARBOR study
| Characteristic | Quartile 1 (≤17 letters) n=307 | Quartile 2 (18–24 letters) n=263 | Quartile 3 (25–32 letters) n=246 | Quartile 4 (≥33 letters) n=268 | Overall p value* |
|---|---|---|---|---|---|
| Age (years) | |||||
| Mean (SD) | 78.6 (9.1) | 78.9 (8.0) | 78.5 (8.0) | 78.9 (8.0) | 0.92 |
| BCVA (letters) | |||||
| Mean (SD) | 47.9 (14.2) | 55.8 (12.8) | 56.0 (11.7) | 57.6 (9.2) | <0.0001 |
| LLVA (letters) | |||||
| Mean (SD) | 36.3 (13.7) | 34.7 (12.8) | 27.8 (12.0) | 15.4 (10.3) | <0.0001 |
| CNV class, n (%) | |||||
| Minimally classic | 116 (37.8) | 112 (42.6) | 137 (55.7) | 138 (51.5) | <0.0001 |
| Occult | 142 (46.3) | 117 (44.5) | 78 (31.7) | 79 (29.5) | |
| Predominantly classic | 49 (16.0) | 34 (12.9) | 31 (12.6) | 51 (19.0) | |
| Total area of CNV (DA) | |||||
| Mean (SD) | 2.8 (2.0) | 2.8 (1.8) | 3.2 (2.1) | 4.0 (2.4) | <0.0001 |
| CFT (µm) | |||||
| Mean (SD) | 354.1 (153.8) | 332.2 (135.2) | 336.0 (130.6) | 349.2 (148.0) | 0.22 |
| Subretinal fluid (µm) | |||||
| Mean (SD) | 96.5 (93.3) | 124.0 (104.7) | 120.8 (105.3) | 171.0 (123.4) | <0.0001 |
*p Value from ANOVA for continuous variables and χ2 for categorical variables.
ANOVA, analysis of variance; BCVA, best-corrected visual acuity; CFT, central foveal thickness; CNV, choroidal neovascularisation; DA, disc area; LLVA, low-luminance visual acuity.