Associations of swept-source optical coherence tomography iris parameters with iris crypt and furrow (n=3297 eyes)
| Model 1 | Model 2 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | β* | p Value for trend | β* | p Value for trend | |
| Crypts | |||||||||
| IT750, mm | 0.36 (0.05) | 0.36 (0.05) | 0.36 (0.06) | 0.37 (0.07) | 0.35 (0.05) | −0.001 | 0.401 | −0.003 | 0.004 |
| IT2000, mm | 0.43 (0.05) | 0.41 (0.05) | 0.39 (0.05) | 0.36 (0.06) | 0.33 (0.05) | −0.009 | <0.001 | −0.010 | <0.001 |
| Iris volume, mm3 | 38.49 (4.09) | 37.14 (3.92) | 35.62 (4.05) | 33.87 (4.08) | 32.5 (4.03) | −0.553 | <0.001 | −0.540 | <0.001 |
| Iris curvature, mm | 0.22 (0.08) | 0.21 (0.08) | 0.2 (0.08) | 0.19 (0.08) | 0.18 (0.08) | −0.004 | 0.005 | −0.003 | 0.030 |
| Furrows | |||||||||
| IT750, mm | 0.35 (0.05) | 0.37 (0.05) | 0.37 (0.05) | NA | NA | 0.004 | <0.001 | 0.004 | <0.001 |
| IT2000, mm | 0.4 (0.06) | 0.42 (0.06) | 0.41 (0.05) | NA | NA | 0.002 | 0.129 | 0.002 | 0.145 |
| Iris volume, mm3 | 36.57 (4.16) | 37.49 (4.27) | 37.93 (4.21) | NA | NA | 0.226 | <0.001 | 0.233 | <0.001 |
| Iris curvature, mm | 0.22 (0.09) | 0.19 (0.1) | 0.19 (0.09) | NA | NA | −0.004 | 0.008 | −0.004 | 0.007 |
Data are mean (SD). Model 1: adjusted for age, sex and ethnicity. Model 2: adjusted for age, sex, ethnicity, pupil size and corneal arcus.
*β represents change in swept-source optical coherence tomography iris parameters for one grade higher in iris crypts or furrow.
IT750, iris thickness 750 µm from scleral spur; IT2000, iris thickness 2000 µm from scleral spur.