Table 5

Top: absolute and relative numbers for how often the two new proposed aberrometry-derived formulae, the LiHue and LiHue/AL, would have calculated a different IOL from the one implanted, how the refractive outcome would have been affected and how accurately astigmatism was measured during aphakia as compared with postoperative refraction at 3 months. Bottom: mean and median prediction errors for three published aphakia formulae (derived from autorefractive retinoscopy), LiHue/AL and LiHue as compared with conventional biometry with the Haigis formula Top

LiHue calculated different
IOL than implanted IOL by
NPer centLiHue IOL would have had better/worse outcome than implanted IOL byNbetter/
Nworse
%better
<−1 D2742.2<−1 D1/109.1
−1 to −0.5 D46.3−1 to −0.5 D1/910.0
−0.5 to 0 D57.8−0.5 to 0 D1/614.3
0 to +0.5 D34.70 to +0.5 D8/753.3
+0.5 to +1 D710.9+0.5 to +1 D7/463.6
>+1 D1828.1> +1 D1/910.0
Totals64100.0Totals19/4529.7
LiHue/AL calculated different
IOL than implanted IOL by
NPer centLiHue/AL IOL would have had better/worse outcome than implanted IOL byNbetter/
Nworse
%better
<−1 D2335.9<−1 D0/70.0
−1 to −0.5 D710.9−1 to −0.5 D2/722.2
−0.5 to 0 D812.5−0.5 to 0 D1/811.1
0 to +0.5 D1015.60 to +0.5 D10/1245.5
+0.5 to +1 D46.3+0.5 to +1 D7/370.0
>+1 D1218.8>+1 D2/528.6
Totals64100.0Totals22/4234.4
IWA cylinder power different
from postop refraction by
NPer centIWA cylinder axis different
from postop refraction by
NPer cent
0 to −0.25 D2442.10–10°47.0
−0.25 to −0.5 D47.010–20°712.3
−0.5 to −0.75 D712.320–30°712.3
−0.75 to −1 D58.8>30°3968.4
<−1 D1729.8
Totals57100.0Totals57100.0
Bottom
Prediction errorLiHue/ALLiHueIanchulev7Leccisotti8Wong9Haigis
Med AE (D) (95% CI)*0.65 (0.45 to 0.89)LiHuILWH0.92 (0.66 to 1.25)3.86 (3.42 to 4.73)3.85 (3.17 to 4.33)3.32 (2.96 to 4.05)0.44 (0.13 to 0.75)
MAE±SD (D)†0.86±0.74LiHuILWH1.15±0.944.13±2.033.96±2.033.57±1.910.55±0.58
% within ±0.5 DZ41ILW2532556
% within ±0.75 DZ55ILW4565867
% within ±1.0 DZ70ILWH5367983
  • *Significant at 0.05 level against formulae indicated by superscript capital letters. Two-sided binomial test of proportions.

  • †Significant at 0.05 level against formulae indicated by superscript capital letters. Paired t test.

  • Z significant at 0.05 level against formulae indicated by superscript. Z-test of proportions.

  • Formula abbreviations in superscript: LiHu, LiHue; I, Ianchulev; L, Leccisotti; W, Wong; H, Haigis.

  • D, dioptres; IOL, intraocular lens; IWA, intraoperative wavefront aberrometry; MAE, mean absolute error; MedAE, median absolute error.