Outcome of ROP treatment with IVB and laser photocoagulation in infants with posterior ROP (zone I and posterior zone II) and peripheral zone II ROP
| Parameter | Posterior zone | Peripheral zone II | p Value | |||
|---|---|---|---|---|---|---|
| Zone I | Zone II | |||||
| IVB | IVB | Laser | IVB | Laser | ||
| Time to complete regression (days) | 9 (6 to 11.5) | 13 (11 to 19) | 57 (28 to 63) | 25 (13.5 to 34.5) | 24 (12 to 45) | <0.001 |
| Visual acuity* (cycle/degree) | 1.45 (0.63 to 4.7) | 4.75 (1.6 to 4.7) | 4.7 (4.7 to 4.7) | 5.55 (1.6 to 9.6) | 4.6 (1.6 to 4.7) | 0.298 |
| Spherical equivalent* (dioptres) | 1.75 (1.25 to 2.5) | 0.12 (−0.75 to 1.75) | 1.0 (−1.5 to 1.5) | 3.0 (2.0 to 4.0) | 1.5 (0.38 to 3.0) | <0.001 |
Data represent n (%) or median (IQR). The p value describes the differences between the patient groups in posterior ROP (zone I and zone II pooled together) versus peripheral zone II ROP. Statistically significant p values are highlighted in bold.
*Pooled data of right and left eyes.
IVB, intravitreal bevacizumab; ROP, retinopathy of prematurity.