Class: NON SELECTIVE ADRENERGIC AGONISTS
| Compound | Mode of action | IOP reduction | Contra-indications | Side effects | |
|---|---|---|---|---|---|
| Non- selective | Epinephrine 0.25-2.0% Dipivefrin 0.1% | Decreases aqueous humour production and may increases uveo-scleral outflow | 15-20% | Occludable angles (iridotomy needed) Aphakic patients (macular oedema) | Local: Conjunctival hyperemia, conjunctival pigmentation. Burning, stinging, ocular pain, blurred vision, macular oedema Systemic: systemic hypertension, headache, anxiety, confusion, chest pain, shortness of breath, tachycardia, sweating |