Table 3.8


CompoundMode of actionIOP reductionContra-indicationsSide effects
OralGlycerol Isosorbide AlcoholDehydration and reduction in vitreous volume Posterior movement of the iris-lens plane with deepening of the AC15-20%Cardiac or renal failureNausea, Vomiting, dehydration (special caution in diabetic patients). Increased diuresis, hyponatremia when severe may lead to lethargy, obtundation, seizure, coma. Possible increase of bood glucose. Acute oliguric renal failure. Hypersensitivity reaction
IntravenousMannitol Urea15-30%