Complications
| Ocular complications | IAC | IVC |
|---|---|---|
| Retinal detachment (secondary): No. eyes | 14 | 14 |
| Total (N surgery) | 9 (6) | 7 (0) |
| Partial (N surgery) | 4 (2) | 5 (0) |
| Peritumoral | 1 | 2 |
| Retinopathy: No. eyes | 8 (32%) | 4 (17.4%) |
| Actinic (radiotherapy plaque-related) | 0 | 4 |
| Ischaemic | 2 | 0 |
| Occlusive choroidopathy | 3 | 0 |
| IViC-related melphalan retinopathy | 3 | 0 |
| Vitreous haemorrhage | 1 | 5 |
| Neovascularisation | 2 | 0 |
| Phthisis bulbi | 0 | 1 |
| Cataract: No. eyes (N surgery) | 6 (0) | 3 (3) |
| Transient ocular adnexa+forehead complications | ||
| Palpebral oedema | 5 | 0 |
| Palpebral erythema | 1 | 0 |
| Ptosis | 1 | 0 |
| Localised frontal hair loss | 1 | 0 |
| Transient systemic complications | ||
| Cardiorespiratory disturbances (No. patients) | 4 | 0 |
| Vasospasm (No. patients): | 2 | 0 |
| Internal carotid and/or ophthalmic artery | 2 | – |
| Neutropenia (No. patients): | 3 | 5 |
| Non-febrile grade 1 | 3 | 2 |
| Febrile grade 3 | 0 | 3 |
| Thrombocytopenia (No. patients) | 0 | 6 |
| Allergy to carboplatin/VP16 (No. patients) | – | 2 |
| Anaemia (No. patients) | 0 | 3 |
| Transfusion: No. patients (N transfusions) | 0 | 8 (11) |
| Blood transfusion | 0 | 3 (3) |
| Transfusion thrombocytes | 0 | 5 (8) |
| Nausea | 4 | 5 |
IAC, intra-arterial chemotherapy; IVC, Intravenous chemotherapy; IViC, intravitreal chemotherapy.