Baseline sociodemographic and clinical data on patients who had treatment and follow-up interruptions and those (control; randomly selected at a rate of 2/100) who had continued with follow-up
| Discontinued with treatment and follow-up [A] (n=123) | Continued with follow-up | P′ [A−B] | P’’ [A−C] | P’’ [B−C] | ||
|---|---|---|---|---|---|---|
| Entire [B] (n = 6 725) | Randomly selected at a rate of 2/100 [C] (n=135) | |||||
| Age (years) | 59.1±8.9 | 55.2±9.3 | 56.1±7.2 | 0.001* | 0.003* | 0.264* |
| Age distribution, n (%) | – | 0.090† | – | |||
| Young (age <40) | 6 (4.9) | – | 10 (7.4) | |||
| Middle (41≤ age <60) | 56 (45.5) | – | 76 (56.3) | |||
| Old (60≤ age) | 61 (49.6) | – | 49 (36.3) | |||
| Gender, n (%) | <0.001‡ | 0.020‡ | 0.080‡ | |||
| Males | 89 (72.4) | 3423 (50.9) | 79 (58.5) | |||
| Females | 34 (27.6) | 3302 (49.1) | 56 (41.5) | |||
| Region, n (%) | – | 0.193‡ | – | |||
| Seoul§ | 83 (67.5) | – | 101 (74.8) | |||
| Province | 40 (32.5) | – | 34 (25.2) | |||
| DM (positive/negative) | 42/81 | – | 45/90 | – | 0.890‡ | – |
| HTN (positive/negative) | 53/70 | – | 55/80 | – | 0.703‡ | – |
| Spherical equivalent (D) | −0.74±3.49 | – | −0.49±3.81 | – | 0.584* | – |
| Intraocular pressure (mmHg)¶ | 12.3±3.9 | – | 16.9±7.4 | – | <0.001* | – |
| CCT (mm) | 536.1±32.3 | – | 532.8±36.0 | – | 0.441* | – |
| Axial length (mm) | 24.4±1.84 | – | 24.7±1.73 | – | 0.178* | – |
| Type of glaucoma diagnosis, n (%) | – | 0.070† | – | |||
| Primary open-angle glaucoma | 107 (87.0) | – | 108 (80.0) | |||
| Primary angle-closure glaucoma | 3 (2.4) | – | 9 (7.4) | |||
| Secondary open-angle glaucoma | 9 (7.3) | – | 11 (8.1) | |||
| Secondary angle-closure glaucoma | 4 (3.3) | – | 7 (5.2) | |||
| VF MD (dB) | −6.17±2.91 | – | −7.27±3.32 | – | 0.005* | – |
| VF PSD (dB) | 8.73±3.80 | – | 9.37±5.01 | – | 0.252* | – |
| Glaucoma disease severity, n (%) | – | 0.235† | – | |||
| Mild stage (MD ≥−6.00 dB) | 96 (78.0) | – | 93 (68.9) | |||
| Moderate stage (−12.00 dB≤MD≤−6.01 dB) | 25 (20.3) | – | 37 (27.4) | |||
| Severe stage (MD≤−12.01 dB) | 2 (1.6) | – | 5 (3.7) | |||
| Follow-up interval (months) | 5.37±1.21 | – | 5.25±1.53 | – | 0.488* | – |
| Classification of patient, n (%) | – | 0.107† | – | |||
| New patient (1≥ visit) | 3 | – | ||||
| Established patient (2≤ visits) | 120 | 135 | ||||
Values are mean±SD.
*Student's t-test.
†Fisher's exact test.
‡χ2 test.
§Including Seoul metropolitan area.
¶Baseline intraocular pressure prior to intraocular pressure-lowering treatment.
CCT, central corneal thickness; D, dioptres; dB, decibels; DM, diabetes mellitus; F, female; HTN, hypertension; M, male; MD, mean deviation; PSD, pattern SD; VF, visual field.