Table 3

Individual druse size, appearance of drusen and cone photoreceptor metrics calculated from AO flood images and SD-OCT

Drusen					Cone metrics								SD-OCT
ID number	Eye	Horizontal druse size (µm)	Vertical druse size (µm)	Druse appearance: number of drusen*	Number of cones		Cone density (cones/mm²)		NND (µm)		Regularity† (%)		RPE-complex thickening‡ (µm)
ID number	Eye	Horizontal druse size (µm)	Vertical druse size (µm)	Druse appearance: number of drusen*	Over druse	Around druse§	Over druse	Around druse	Over druse	Around druse	Over druse	Around druse	RPE-complex thickening‡ (µm)
5008	OD	22.1	22.1	Round: 1	41	40	54 572	52 908	3.56	3.61	90	94	–
5009	OS	23.7	23.7	Round: 1	19	17	22 072	19 517	5.42	5.73	84	93	–
5009	OS	23.7	23.7	Round: 1	9	11	10 455	12 779	6.75	7.07	89	93	–
5005	OD	26.6	23.6	Oval: 1	10	13	11 674	14 943	5.46	5.90	90	88	4
5009	OS	26.6	26.6	Round: 1	10	13	11 617	14 812	7.10	5.94	90	90	–
5010	OS	30.6	33.7	Round: 1	13	13	12 772	12 527	5.45	6.54	92	94	7
5001	OD	30.8	30.8	Round: 1	20	21	21 379	21 914	5.25	5.33	90	89	4
5013	OD	32.0	29.1	Round: 1	9	11	9 785	11 416	6.17	6.43	67	90	–
5014	OD	33.5	33.5	Round: 1	32	33	28 416	28 949	4.65	4.72	84	93	–
5001	OS	34.0	40.2	Lobular: 2	38	41	27 822	29 872	4.60	4.68	92	94	7
5012	OD	36.1	27.8	Oval: 1	117	118	30 979	32 727	4.11	4.11	87	85	–
5007	OS	39.2	51.3	Lobular: 2	39	42	19 280	20 763	5.17	5.67	87	95	8
5008	OD	55.3	33.2	Lobular: 3	31	34	16 895	18 530	5.94	5.79	100	90	4
5012	OD	61.1	36.1	Lobular: 3	31	33	52 892	53 495	3.63	3.70	95	97	4

↵*Suggested number of drusen that have fused together.
↵†Regularity is the percentage of cones with 5, 6 or 7 neighbours.
↵‡Difference in RPE complex thickness measured in drusen area and RPE complex thickness in the control area.
§Control area, mean of 4–6 adjacent locations where a contiguous cone mosaic was clearly visible.
NND, nearest neighbour distance; OD, oculus dexter; OS, oculus sinister; RPE, retinal pigment epithelium cell.