Youden index applied		Sensitivity (%)		Specificity (%)
IgG2 >48 positive cells		58.1		76.9
IgG2:IgG ratio >9.3%		93.0		41.7
Serum IgG2 >5.3 g/L		80.0		91.7
Serum IgG4 >0.63 g/L		75.0		66.7