Table 1

Growth of meibomian glands post-MGP

A B C D E F G H I J K L M N O
Case Lid Atrophy grade Post-MGP follow-up (months) Glands analysed (n) Pre-MGP total glandular area:
([total gland area / TMF] × 100) (%)
Post-MGP total glandular area:
([total gland area / TMF] ×  100) (%)
Percentage point difference:
(G–F)
% Growth in total gland area (per lid):
(H / F) ×  100
Pre-MGP mean individual gland area:
([mean individual gland Area / TMF] ×  100) (%)
Post-MGP mean individual gland area:
([mean individual gland area / TMF] × 100) (%)
Percentage point difference:
(K–J)
% Growth in mean individual gland area:
(L / J) × 100
p Value (individual gland area post-MGP vs pre-MGP comparison) Type(s) of growth seen on at least one MG/lid, within the TMF, using IR-M
Follow-up at ≤12 months
004 LU211.5 1331.7435.65 3.91 12.322.442.74 0.3012.30 0.1637Increased density
007 RU2 8.5 1329.4129.80 0.39 1.332.262.29 0.03 1.33 0.8523Increased density and proximal lengthening
007 (3) LU 3 8.5  15 21.37 25.78  4.41 20.61 1.42 1.72 0.30 21.13 0.0277 Increased density, proximal lengthening, and new gland tissue
011 RU1 5.3 1041.2236.41−4.81−11.674.123.64−0.48−11.65 0.0975Proximal lengthening
013 RU1 5.8 940.5239.21−1.31 −3.234.504.36−0.14−3.11 0.4507Increased density
016 RU2 4.5 1236.5035.57−0.93 −2.553.042.97−0.07−2.30 0.7250Increased density/stoutness
018 RU1 6.9 NANANA NA NANANA NA NA NAIncreased density
020 RU2 7.0 NANANA NA NANANA NA NA NAIncreased density
022 LU1 4.6 NANANA NA NANANA NA NA NAIncreased density
024 RU 2 5.3 12 40.31 48.06 7.75 19.23 3.36 4.01  0.65 19.35 <0.0001 Lengthening
025 RU1 7.6 1247.9848.50 0.52 1.084.004.04 0.04 1.00 0.8651Distal and proximal lengthening
027 (2) RU 2 11.3 9 26.62 30.53  3.91 14.69 2.96 3.39 0.43 14.53 0.0345 Increased density and proximal lengthening
029 RU3 7.1 NANANA NA NANANA NA NA NAIncreased density
034 LU 1 5.1  11 41.12 45.52  4.4 10.70 3.74 4.14 0.40 10.70 0.0292 Discontinuous -> continuous
All lids ≤12 months NA NA NA 116 35.68 37.50  1.82 5.10 3.08 3.23 0.15  4.87 0.0145
Follow-up at >12 months
003 RU120.5 1131.2130.82−0.39 −1.252.842.80−0.04−1.41 0.8029Discontinuous -> continuous
026 LU112.5 NANANA NA NANANA NA NA NADiscontinuous -> continuous
032 (1) RU 1 24.9 11 32.48 38.96  6.47  19.93 2.95 3.54 0.59 20.00  0.0001 Proximal lengthening
032 LU 1 24.9 11 33.62 38.33  4.71 14.01 3.06 3.48 0.42 13.73  0.0097 Proximal lengthening
All lids >12 months NA NA NA  33 32.44 36.04  3.6 11.10 2.95 3.28 0.31 11.19  0.0004
All follow-ups (4.5–25 months)
Total NA NA NA 149 34.93 37.16  2.23  6.38* 3.05 3.24  0.19  6.23  0.0003
  • (1)–(3): Lids represented in case studies and in figures 2–4.

  • *p=0.0447.

  • IR-M, infrared meibography; LU, left upper lid; MG, meibomian gland; MGP, meibomian gland probing; NA, not applicable/image not sufficient for quantitative analysis; RU, right upper lid; TMF, total measurement field. Discontinuous → Continuous indicates restoration of a continuous gland from discontinuous segments.