Table 1

Clinical features, visual field parameters and vessel density measurements of the participants

Control group (42 eyes, 27 subjects)Glaucoma group (45 eyes, 26 patients)p Value
Age (years)*57.4 (39.2–60.4)58.9 (55.3–64.3)0.23
Gender (male:female)16:1123:30.02
Sphere (D)*0.5 (0–1)0.75 (0–1.5)0.09
Cylinder (D)*−0.75 (−1 to 0)0 (−0.75 to 0)0.04
Pseudophakia (n, %)8 (19.1%)6 (13.3%)0.47
IOP at the scanning visit (mm Hg)14.8±2.816.2±3.70.06
Hypertension (yes:no)7:2012:140.15
Diabetes mellitus (yes:no)4:2313:130.01
Mean deviation (dB)*−2.4 (−3.7 to –0.2)−4.7 (−11.0 to –2.6)<0.001
Pattern SD (dB)*1.8 (1.4 to 2.6)3.2 (1.7 to 9.0)<0.001
Visual field index (%)*98 (97 to 100)95 (72 to 98)<0.001
OCTA parameters
SSI (optic disc scan)58.1±6.457.1±5.70.50
Whole enface vessel density (disc scan, %)52.3±3.149.3±5.40.01
Average peripapillary vessel density (%)61.5±3.958.3±5.40.008
 Nasal vessel density (%)58.8±4.457.0±4.10.10
 Inferonasal vessel density (%)62.8±4.057.4±8.10.002
 Inferotemporal vessel density (%)65.0±4.356.4±12.40.001
 Superotemporal vessel density (%)65.8±4.761.5±9.30.03
 Superonasal vessel density (%)59.9±5.057.0±6.90.05
 Temporal vessel density (%)61.4±4.960.1±4.20.22
SSI (macula scan)62.9±4.961.3±6.50.27
Whole enface vessel density (macula scan, %)46.4±3.944.2±4.80.04
Parafoveal vessel density (%)48.7±4.246.4±5.00.04
 Temporal vessel density (%)48.5±4.246.0±5.20.03
 Superior vessel density (%)49.1±4.247.2±5.20.11
 Nasal vessel density (%)48.3±4.146.7±4.70.13
 Inferior vessel density (%)49.1±4.845.8±5.70.01
  • All values represent mean ± SD unless specified.

  • *Median and IQR.

  • IOP, intraocular pressure; OCTA, optical coherence tomography angiography; SSI, signal strength index.