Results of cytological tests performed in healthy controls and in patients with psoriasis (also divided in arthritic and not arthritic and in treated and not treated with biological drugs).
Conjunctival impression cytology | Controls (n=28) | Psoriasis, (n=66) | Arthritis, (n=26) | No arthritis, (n=40) | Biological treatment, (n=30) | No biological treatment, (n=36) |
Cellularity | 0.5±0.7 | 1±0.7* | 0.9±0.8* | 1±0.6* | 0.9±0.7* | 1±0.7* |
N/C | 0.5±0.5 | 0.9±0.4* | 0.9±0.5* | 0.9±0.3* | 1±0.3* | 0.8±0.4* |
Chromatin | 0.7±0.5 | 1.1±0.3* | 1.1±0.5* | 1.1±0.3* | 1.1±0.3* | 1.1±0.4* |
Cell-to-cell contacts | 0.2±0.4 | 1.2±0.6* | 1.2±0.6* | 1.2±0.6* | 1.1±0.6* | 1.3±0.6* |
Goblet cells | 0.3±0.5 | 0.9±0.6* | 1.1±0.6*† | 0.8±0.5* | 1.1±0.5* | 0.9±0.6* |
Keratinisation | 0 | 1±0.8* | 0.9±0.8* | 1.1±0.8* | 0.9±0.7* | 1±0.7* |
Inflammatory cells | 0 | 0.1±0.3 | 0.1±0.5 | 0 | 0.1±0.4 | 0.1±0.3 |
Total score | 2.2±1.3 | 6.2±1.9* | 6.3±2.3* | 6.1±1.5* | 6.2±1.8* | 6.2±2* |
↵*p<0.05 versus controls; †p=0.03 versus no arthritis.
N/C, nucleus/cytoplasm ratio.