Inclusion and exclusion criteria to the LiGHT Trial
| Inclusion criteria | Exclusion criteria |
| Newly diagnosed and untreated POAG or OHT* with a decision to treat† made by a consultant ophthalmologist‡ | Advanced POAG§ |
| 18 years or older | Visual acuity worse than 6/36 in a study eye¶ |
| Able to provide informed consent | Secondary glaucoma** |
| Able to understand English | Angle closure |
| Congenital/early childhood glaucoma | |
| Previous treatment for POAG/OHT | |
| Contraindication to SLT | |
| Inability to use topical medical therapy | |
| Visually significant cataract | |
| Active treatment for another ophthalmic condition in either eye | |
| History of retinal ischaemia, macular oedema or diabetic retinopathy | |
| Age-related macular degeneration with neovascularisation or geographic atrophy | |
| Previous intraocular surgery†† | |
| Pregnancy or intention to become pregnant | |
| Medically unfit for completion of the trial | |
| Involvement in another interventional research study |
*In one or both eyes (including pseudoexfoliation glaucoma).
†Under the National Institute for Health and Care Excellence guidelines.11
‡Fellowship-trained glaucoma subspecialist consultant ophthalmologist.
§Visual field loss mean deviation worse than −12 dB in the better or −15 dB in the worse eye.
¶Uniocular patients were eligible.
**Pigment dispersion syndrome, trauma.
††Except uncomplicated phacoemulsification at least 1 year before entering the trial.
LiGHT, Laser in Glaucoma and Ocular Hypertension; OHT, ocular hypertension; POAG, primary open-angle glaucoma; SLT, selective laser trabeculoplasty.