Table 2

Adverse events in year 2 of ENDURANCE

Eventsn (%)
Ocular adverse events
 Vitreous haemorrhage6 (11)
 Neovascularisation in the mid-periphery3 (6)
 Neovascularisation of the disc1 (2)
 Worsening cataract2 (4)
 Corneal abrasion1 (2)
 Subconjunctival haemorrhage1 (2)
 Superficial punctate keratitis1 (2)
 Eye swelling post-cataract extraction1 (2)
 Posterior vitreous detachment1 (2)
 Floaters2 (4)
 Visual disturbance1 (2)
 Epiphora1 (2)
 Posterior capsule opacification1 (2)
 Iritis1 (2)
 Eye pain1 (2)
 Vitreous debris1 (2)
Serious adverse events
 Death (myocardial infarction)1 (2)
 Stroke1 (2)
 Deep vein thrombosis1 (2)
 Worsening congestive heart failure1 (2)
 Acute vision loss secondary to vitreous haemorrhage2 (4)
 Acute vision loss due to worsening cataract1 (2)
 Worsening staph infection with low blood count1 (2)
 Acute gastroenteritis1 (2)
 Cellulitis1 (2)
 Non-fatal myocardial infarction1 (2)