Risk factors for failure (increase in IOP or need for glaucoma surgery)
| Cox’s proportional hazard model on time to event (risk factors for complete failure) | ||||
| Univariate | Multivariate | |||
| Crude HR (95% CI) | Crude p value | Adjusted HR (95% CI) | p Value | |
| Age*: Reference=cluster A | ||||
| Cluster B | 0.49 (0.2 to 1.17) | 0.109 | 0.13 (0.03 to 0.5) | 0.003 |
| Cluster C | 0.63 (0.21 to 1.92) | 0.419 | 0.12 (0.03 to 0.55) | 0.006 |
| Preoperative IOP†: reference=group A | ||||
| Group B | 1.04 (0.3 to 3.57) | 0.947 | 0.38 (0.1 to 1.5) | 0.169 |
| Group C | 6.27 (1.92 to 20.43) | 0.002 | 4.1 (1.08 to 15.54) | 0.038 |
| CDR (preoperative) | 1.4 (0.24 to 8.08) | 0.708 | 22.21 (1.68 to 93.) | 0.019 |
| No of AGM (preoperative) | 1.72 (1.09 to 2.72) | 0.02 | 1.62 (0.93 to 2.8) | 0.086 |
*Preoperative age was divided into three clusters by quantile distribution. Cluster A ranged from 2 to 6 years, cluster B ranged from 7 to 18 years and cluster C was ≥19 years age during surgery.
†By K-means clustering technique, the preoperative IOP was divided into three groups. Group A: IOP less than 19 mm Hg, group B: IOP 20–32 mm Hg and group C: IOP >32 mm Hg.
AGM, antiglaucoma medication; CDR, cup to disc ratio; IOP, intraocular pressure.