Comparison(ClinicalTrial.gov identifier) | Year | Duration(months) | Number of patients | Study type | Results |
Travoprost (sofZia) vs Latanoprost BAK(NCT00798759) | 2008 | 3 | 215 | Double masked RCT | OSDI score slightly better with SofZiaTBUT the same |
Travoprost (sofZia) vs Latanoprost BAK(NCT00690794) | 2008 | 3 | 726 | Double masked RCT | OSDI change similarAbsence of corneal staining similar (37 sofZia, 40 BAK) |
Travoprost (sofZia) vs Latanoprost BAK(NCT00527592) | 2007 | Not stated | 54 (comparison made between eyes) | Double masked RCT | Comfort after dose equal |
BAK, benzalkonium chloride; OSDI, Ocular SurfaceDisease Index; RCT, randomised controlled trials; TBUT, tear breakup time.