Table 2

The correlation between OCT angiography parameters and spectral domain OCT parameters or VFSS

Peripapillary vessel densityParafoveal vessel density
AverageNINITSTSNTAverageSuperiorInferiorTSNI
(A) NMOSD+ON group
 RNFL averageB2.0701.9181.6321.7291.5901.3051.5091.4411.1321..6470.8611.2450.2961.896
P0.000*0.000*0.000*0.000*0.000*0.000*0.000*0.013*0.047*0.006*0.1670.026*0.5690.000*
 GCC averageB1.3911.0951.0841.1501.0390.8361.1671.3341.1011.4070.8661.0490.4621.516
P0.000*0.000*0.000*0.000*0.000*0.000*0.000*0.002*0.006*0.002*0.0760.005*0.1780.000*
 GCIPL averageB0.3670.3450.2710.2200.3920.1260.3430.9680.8080.9460.9210.5630.5430.721
P0.0780.0580.2660.3650.0630.4150.024*0.0600.0770.0700.0980.1550.1100.086
 VFSSB−2.906E-005−2.991E-005−2.543E-005−2.667E-005−3.233E-005−1.521E-005−1.578E-005−1.896E-005−1.768E-005−1.799E-005−2.692E-005−9.765E-006−1.676E-005−5.767E-006
P0.026*0.030*0.011*0.034*0.026*0.0520.033*0.2230.1870.2740.2160.3090.2990.583
(B) NMOSD-ON group
 RNFL averageB0.6140.6600.3600.2890.1390.0820.082−0.085−0.085−0.085−0.085−0.0370.029−0.116
P0.0550.001*0.024*0.1150.4710.6920.6140.5480.9030.8760.7100.7380.8740.221
 GCC averageB0.2420.2660.148−0.0410.081−0.0190.1180.1730.1790.132−0.2200.1250.1630.061
P0.1030.016*0.1080.6550.2970.7020.2200.046*0.028*0.0790.021*0.030*0.1310.264
 GCIPL averageB0.1620.2010.2040.0190.131−0.096−0.065−0.0210.048−0.0810.0400.0030.030−0.080
P0.4800.1460.0640.9150.3680.3580.9370.8570.6770.5230.7100.9760.8300.446
  • *With statistical significance (p<0.05).

  • B, regression coefficient in generalised estimating equation models; GCC, ganglion cell complex; GCIPL, parafoveal ganglion cell and inner plexiform layer; I, inferior; IN, inferior nasal; IT, inferior temporal; N, nasal; NMOSD, neuromyelitis optica; OCT, optical coherence tomography; ON, optic neuritis; RNFL, retinal nerve fibre layer; S, superior; SN, superior nasal; ST, superior temporal; T, temporal; VFSS, visual functional system score.