Retinal layer thickness of study population evaluated on structural spectral-domain optical coherence tomography
| Group 1 | Group 2 | Group 3 | Control group | P value* | P value† | P value‡ | P value§ | P value¶ | P value** | |
| CRT | 321.8±16.67 | 322.6±30.22 | 318.4±17.44 | 334±12.64 | >0.9 | >0.9 | 0.2 | 0.9 | 0.3 | 0.07 |
| RPE | 17.30±2.98 | 17.54±3.61 | 23.01±6.13 | 15.02±1.16 | >0.9 | <0.0001†† | 0.2 | 0.0001†† | 0.2 | <0.0001†† |
| ONL | 67.78±8.62 | 62.83±14.50 | 66.66±9.39 | 73.51±6.96 | 0.4 | >0.9 | 0.3 | 0.6 | 0.007†† | 0.1 |
| OPL | 33.01±3.90 | 31.45±3.92 | 32.65±3.65 | 33.94±3.88 | 0.5 | >0.9 | 0.8 | 0.7 | 0.2 | 0.7 |
| INL | 37.71±3.98 | 37.93±4.50 | 35.96±3.19 | 38.76±3.40 | >0.9 | 0.4 | 0.8 | 0.3 | 0.9 | 0.1 |
| IPL | 36.4±4.22 | 36.27±4.96 | 35.25±4.54 | 39.46±2.56 | >0.9 | 0.8 | 0.09 | 0.8 | 0.07 | 0.009†† |
| GCL | 41.91±5.86 | 42.28±6.2 | 41.19±6.25 | 47.06±3.58 | >0.9 | 0.9 | 0.02†† | 0.9 | 0.03†† | 0.006†† |
| RNFL | 20.45±2.19 | 20.91±2.48 | 19.66±2.14 | 19.49±1.49 | 0.9 | 0.6 | 0.5 | 0.2 | 0.2 | 0.9 |
Group 1, reticular pseudodrusen (RPD); Group 2, RPD+outer retinal atrophy; Group 3, drusen.
Retinal layer thickness was reported using ETDRS macular map with the central subfield 1 mm in diameter and the outer subfields having diameters of 3 mm. Each value is expressed as mean±SD. All the P values refer to one-way analysis of variance with Bonferroni correction and multiple comparison between groups.
*Comparison between group 1 and group 2.
†Comparison between group 1 and group 3.
‡Comparison between group 1 and control group.
§Comparison between group 2 and group 3.
¶ Comparison between group 2 and control group.
**Comparison between group 3 and control group.
††Statistically significant value.
CRT, central retinal thickness; GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; ONL, outer nuclear layer; OPL, outer plexiform layer; RNFL, retinal nerve fibre layer; RPE, retinal pigment epithelium.