Comparison of demographic characters between the patients with MOG-ON and AQP4-ON
| MOG-ON | AQP4-ON | P value | |
| Number of patients (N) | 20 | 45 | |
| Number of affected eyes (N, %) | 34/40, 68 | 75/90, 83.3 | 0.812* |
| Ethnicity (Han Chinese) N, %) | 20/20, 100 | 44/45, 97.8 | 0.692† |
| Sex (female, N, %) | 14/20, 70 | 42/45, 93.3 | 0.034* |
| Age (years, mean±SD) | |||
| At first attack | 20.2 (17.4) | 35.6 (15.7) | 0.001‡ |
| At sampling | 22 (17.5) | 39.7 (15.2) | <0.001‡ |
| Age at first attack <18 years (N, %) | 13/20, 65 | 5/45, 11 | <0.001* |
| Observation time (months, mean±SD) | 29.0±32.5 | 51.0±65.9 | 0.076‡ |
*Pearson χ2 test.
†Fisher’s exact test.
‡Independent t-test.
AQP4, aquaporin-4; AQP4-ON, AQP4 antibody-associated ON; MOG, myelin oligodendrocyte glycoprotein; MOG-ON, MOG antibody-associated ON; ON, optic neuritis.