Characteristics | Change in IOP (mm Hg) | |||
β (95% CI) | ||||
All (n=3188 persons; 6376 eyes)† | Subgroup 1 (n=907 persons; 1814 eyes)‡ | Subgroups 2 and 3 (n=2140 persons; 4280 eyes)† | Subgroup 4 (n=141 persons; 282 eyes)‡ | |
Model with SBP | ||||
Baseline SBP, per 10 mm Hg | 0.20 (0.14 to 0.26)** | 0.31 (0.12 to 0.50)* | 0.16 (0.09 to 0.24)** | −0.04 (−0.55 to 0.45) |
Change in SBP, per 10 mm Hg | 0.27 (0.21 to 0.33)** | 0.31 (0.20 to 0.57)** | 0.24 (0.17 to 0.31)** | 0.26 (−0.18 to 0.71) |
Antihypertensive medications | ||||
Neither examinations | Reference | – | Reference | Reference |
Baseline only | 0.43 (−0.01 to 0.97) | – | 0.62 (0.02 to 1.23)* | −1.34 (−2.81 to 0.13) |
Follow-up only | −0.01 (−0.23 to 0.27) | – | −0.04 (−0.36 to 0.28) | – |
Both examinations | 0.02 (−0.23 to 0.27) | – | 0.01 (−0.29 to 0.30) | – |
Model with DBP | ||||
Baseline DBP, per 10 mm Hg | 0.33 (0.22 to 0.44)** | 0.29 (0.01 to 0.59)* | 0.27 (0.14 to 0.41)** | 0.14 (−0.53 to 0.81) |
Change in DBP, per 10 mm Hg | 0.52 (0.41 to 0.63)** | 0.57 (0.27 to 0.87)** | 0.45 (0.32 to 0.58)** | 0.67 (0.06 to 1.28)* |
Antihypertensive medications | ||||
Neither examinations | Reference | – | Reference | Reference |
Baseline only | 0.47 (−0.06 to 1.01) | – | 0.60 (0.01 to 1.21)* | −1.12 (−2.22 to −0.02)* |
Follow-up only | 0.05 (−0.22 to 0.33) | – | −0.07 (−0.39 to 0.25) | – |
Both examinations | 0.06 (−0.18 to 0.31) | – | −0.03 (−0.32 to 0.26) | – |
Subgroups refer to hypertensive status: subgroup 1: normotensive at baseline and follow-up; subgroup 2: normotensive at baseline and hypertensive at follow-up; subgroup 3: hypertensive at baseline and follow-up; and subgroup 4: hypertensive at baseline and normotensive at follow-up.
*Denotes P<0.05.
**Denotes P<0.001.
†Model with SBP (or DBP) adjusted for age, gender, ethnicity, IOP, body mass index, diabetes, SBP (or DBP), change in SBP (or change in DBP) and antihypertensive medications.
‡Model with SBP (or DBP) adjusted for age, gender, ethnicity, IOP, body mass index, diabetes, SBP (or DBP) and change in SBP (or change in DBP).
–, data were intentionally omitted; DBP, diastolic blood pressure; IOP, intraocular pressure; SBP, systolic blood pressure.