Table 4

Changes between baseline and month 24 in ETDRS level, by study endpoint

PhenotypeEndpoint# PatientsDR worseningDR improvingNo change
All≥3 stepsTwo stepsOne stepAllOne stepTwo steps≥3 steps
A (n=87)No CIMO86 (98.9%)17 (19.8)041330 (34.9)1311639 (45.3)
CIMO1 (1.1%)0 (0.0)0000 (0.0)0001 (100.0)
B (n=45)No CIMO32 (71.1%)2 (6.3)0028 (25.0)60222 (68.8)
CIMO13 (28.9%)2 (15.4)1013 (23.1)1028 (61.5)
C (n=17)No CIMO12 (70.6)4 (33.3)0312 (16.7)1016 (50.0)
CIMO5 (29.4%)3 (60.0)2100 (0.0)0002 (40.0)
  • CIMO, central-involved macular oedema; DR, diabetic retinopathy; ETDRS, Early Treatment Diabetic Retinopathy Study.